Endocrine Abstracts

Use of SGLT2 inhibitors are increasing worldwide due to its potential antihyperglycemic role. Additionally they have shown to be beneficial in reducing the cardiac and renal complications in diabetes. There are sporadic reports to show their effects on liver enzymes. We did a single centre, open label, prospective trial to evaluate the role of dapagliflozin on hepatic enzymes in diabetic patients with non alcoholic fatty liver disease (NAFLD). Abdominal sonography was used to ...

DPP4 inhibitors are special class of drugs that not only improve metabolism in a glucose dependant manner, but also suppress the glucagon axis. Due to its glucose dependant insulinotropic action, vildagliptin is thought to be relatively safe for people who are at risk of developing low glucose episodes. We studied the glucose lowering potential and hypoglycemic effects of vildagliptin among elderly diabetics who were uncontrolled with at least 2 oral antidiabetic medications. ...